Pyridoxal phosphate site in glycogen phosphorylase b: structure in native enzyme and in three derivatives with modified cofactors.

The detailed environment of the essential cofactor pyridoxal 5'-phosphate in glycogen phosphorylase b, resulting from crystallographic refinement at 1.9-A resolution, is described. The pyridoxal ring is buried in a nonpolar site containing three aromatic rings while the 5'-phosphate group...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Oikonomakos, N, Johnson, L, Acharya, K, Stuart, D, Barford, D, Hajdu, J, Varvill, K, Melpidou, A, Papageorgiou, T, Graves, D
פורמט: Journal article
שפה:English
יצא לאור: 1987