In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours
Objectives Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quanti...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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British Editorial Society of Bone and Joint Surgery
2012
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| _version_ | 1826292527927394304 |
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| author | Kwon, Y Mellon, S Monk, P Murray, D Gill, H |
| author_facet | Kwon, Y Mellon, S Monk, P Murray, D Gill, H |
| author_sort | Kwon, Y |
| collection | OXFORD |
| description | Objectives Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities.Methods The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient’s specific hip joint centre, based on CT scans.Results Edge-loading in the hips with pseudotumours occurred with a four-fold increase in duration and magnitude of force compared with the hips without pseudotumours (p = 0.02).Conclusions The study provides the first in vivo evidence to support that edge-loading is an important mechanism that leads to localised excessive wear (edge-wear), with subsequent elevation of metal ion levels in MoMHRA patients with pseudotumours. |
| first_indexed | 2024-03-07T03:16:05Z |
| format | Journal article |
| id | oxford-uuid:b5d29540-f23a-43be-a826-5d7225f014c0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T03:16:05Z |
| publishDate | 2012 |
| publisher | British Editorial Society of Bone and Joint Surgery |
| record_format | dspace |
| spelling | oxford-uuid:b5d29540-f23a-43be-a826-5d7225f014c02022-03-27T04:36:31ZIn vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumoursJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b5d29540-f23a-43be-a826-5d7225f014c0EnglishSymplectic Elements at OxfordBritish Editorial Society of Bone and Joint Surgery2012Kwon, YMellon, SMonk, PMurray, DGill, HObjectives Pseudotumours (abnormal peri-prosthetic soft-tissue reactions) following metal-on-metal hip resurfacing arthroplasty (MoMHRA) have been associated with elevated metal ion levels, suggesting that excessive wear may occur due to edge-loading of these MoM implants. This study aimed to quantify in vivo edge-loading in MoMHRA patients with and without pseudotumours during functional activities.Methods The duration and magnitude of edge-loading in vivo was quantified during functional activities by combining the dynamic hip joint segment contact force calculated from the three-dimensional (3D) motion analysis system with the 3D reconstruction of orientation of the acetabular component and each patient’s specific hip joint centre, based on CT scans.Results Edge-loading in the hips with pseudotumours occurred with a four-fold increase in duration and magnitude of force compared with the hips without pseudotumours (p = 0.02).Conclusions The study provides the first in vivo evidence to support that edge-loading is an important mechanism that leads to localised excessive wear (edge-wear), with subsequent elevation of metal ion levels in MoMHRA patients with pseudotumours. |
| spellingShingle | Kwon, Y Mellon, S Monk, P Murray, D Gill, H In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours |
| title | In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours |
| title_full | In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours |
| title_fullStr | In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours |
| title_full_unstemmed | In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours |
| title_short | In vivo evaluation of edge-loading in metal-on-metal hip resurfacing patients with pseudotumours |
| title_sort | in vivo evaluation of edge loading in metal on metal hip resurfacing patients with pseudotumours |
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