Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice.

Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice.

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Treatment with monoclonal antibodies (mAbs) specific for CD25 (anti-CD25 mAb) has been shown to suppress growth of a variety of different tumours in mice. These studies did not however determine whether or not anti-CD25 mAbs facilitate tumour rejection by depletion of regulatory T cells or by bindin...

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Bibliographische Detailangaben
Hauptverfasser:	Jones, E, Dahm-Vicker, M, Simon, A, Green, A, Powrie, F, Cerundolo, V, Gallimore, A
Format:	Journal article
Sprache:	English
Veröffentlicht:	2002

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