Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice.
Treatment with monoclonal antibodies (mAbs) specific for CD25 (anti-CD25 mAb) has been shown to suppress growth of a variety of different tumours in mice. These studies did not however determine whether or not anti-CD25 mAbs facilitate tumour rejection by depletion of regulatory T cells or by bindin...
Κύριοι συγγραφείς: | Jones, E, Dahm-Vicker, M, Simon, A, Green, A, Powrie, F, Cerundolo, V, Gallimore, A |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2002
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Depletion of CD25+ regulatory cells results in suppression of melanomagrowth and induction of autoreactivity in mice
ανά: Jones, E, κ.ά.
Έκδοση: (2002) -
Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens.
ανά: Golgher, D, κ.ά.
Έκδοση: (2002) -
The influence of CD25+ cells on the generation of immunity to tumour cell lines in mice.
ανά: Jones, E, κ.ά.
Έκδοση: (2004) -
Induction of inflammatory bowel disease in immunodeficient mice by depletion of regulatory T cells.
ανά: Read, S, κ.ά.
Έκδοση: (2001) -
Controlling Autoreactivity of CD4 T Cells by Local Tolerance Induction
ανά: Irmgard FöRster
Έκδοση: (1998-01-01)