Effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis
Vitamin D has biological effects on multiple knee joint structures and data from observational studies suggest vitamin D deficiency may be linked with pain and progression of knee OA. In the UK VIDEO study, a multicentre 3-year randomised placebo controlled trial of vitamin D therapy (800 IU/day) in...
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| Format: | Conference item |
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Elsevier
2018
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| _version_ | 1826292541370138624 |
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| author | Perry, TA O'Neill, TW Parkes, MJ Felson, DT Hodgson, R Arden, NK |
| author_facet | Perry, TA O'Neill, TW Parkes, MJ Felson, DT Hodgson, R Arden, NK |
| author_sort | Perry, TA |
| collection | OXFORD |
| description | Vitamin D has biological effects on multiple knee joint structures and data from observational studies suggest vitamin D deficiency may be linked with pain and progression of knee OA. In the UK VIDEO study, a multicentre 3-year randomised placebo controlled trial of vitamin D therapy (800 IU/day) in patients with symptomatic knee OA, there was no evidence of an effect of vitamin D therapy on either pain or structural progression of disease as assessed using x-rays. We hypothesised, however, that there may be an effect of treatment on the occurrence of synovial tissue volume (STV) and bone marrow lesions (BMLs), as assessed by magnetic resonance imaging (MRI). |
| first_indexed | 2024-03-07T03:16:18Z |
| format | Conference item |
| id | oxford-uuid:b5e95bbd-c2c4-4a5c-8ecf-8015bfe18717 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T03:16:18Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:b5e95bbd-c2c4-4a5c-8ecf-8015bfe187172022-03-27T04:36:57ZEffect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritisConference itemhttp://purl.org/coar/resource_type/c_5794uuid:b5e95bbd-c2c4-4a5c-8ecf-8015bfe18717Symplectic Elements at OxfordElsevier2018Perry, TAO'Neill, TWParkes, MJFelson, DTHodgson, RArden, NKVitamin D has biological effects on multiple knee joint structures and data from observational studies suggest vitamin D deficiency may be linked with pain and progression of knee OA. In the UK VIDEO study, a multicentre 3-year randomised placebo controlled trial of vitamin D therapy (800 IU/day) in patients with symptomatic knee OA, there was no evidence of an effect of vitamin D therapy on either pain or structural progression of disease as assessed using x-rays. We hypothesised, however, that there may be an effect of treatment on the occurrence of synovial tissue volume (STV) and bone marrow lesions (BMLs), as assessed by magnetic resonance imaging (MRI). |
| spellingShingle | Perry, TA O'Neill, TW Parkes, MJ Felson, DT Hodgson, R Arden, NK Effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis |
| title | Effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis |
| title_full | Effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis |
| title_fullStr | Effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis |
| title_full_unstemmed | Effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis |
| title_short | Effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis |
| title_sort | effect of vitamin d therapy on synovial tissue volume and bone marrow lesions in symptomatic knee osteoarthritis |
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