Deregulated DNA ADP-ribosylation impairs telomere replication

Deregulated DNA ADP-ribosylation impairs telomere replication

The recognition that DNA can be ADP ribosylated provides an unexpected regulatory level of how ADP-ribosylation contributes to genome stability, epigenetics and immunity. Yet, it remains unknown whether DNA ADP-ribosylation (DNA-ADPr) promotes genome stability and how it is regulated. Here, we show...

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Bibliographic Details
Main Authors:	Wondisford, AR, Lee, J, Lu, R, Schuller, M, Groslambert, J, Bhargava, R, Schamus-Haynes, S, Cespedes, LC, Opresko, PL, Pickett, HA, Min, J, Ahel, I, O’Sullivan, RJ
Format:	Journal article
Language:	English
Published:	Nature Research 2024

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