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Lenalidomide up-regulates SPARC and inhibits in vitro growth of the malignant clone in myelodysplastic syndrome patients with 5q deletion.

Lenalidomide up-regulates SPARC and inhibits in vitro growth of the malignant clone in myelodysplastic syndrome patients with 5q deletion.

Dades bibliogràfiques
Autors principals: Pellagatti, A, Jadersten, M, Forsblom, A, Cattan, H, Christensson, B, Emanuelsson, E, Merup, M, Nilsson, L, Samuelsson, J, Sander, B, Wainscoat, J, Boultwood, J, Hellstrom-Lindberg, E
Format: Conference item
Publicat: 2006
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  • Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
    per: Pellagatti, A, et al.
    Publicat: (2007)
  • Lenalidomide selectively inhibits in vitro growth of the malignant clone in myelodysplastic syndrome (MDS) patients with 5q deletion.
    per: Jadersten, M, et al.
    Publicat: (2005)
  • Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression.
    per: Jädersten, M, et al.
    Publicat: (2009)
  • Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression
    per: Martin Jädersten, et al.
    Publicat: (2009-12-01)
  • Del(5q) Myelodysplastic Stem Cells Exhibit Their Clonal Advantage Via Increased Adhesion to the Microenvironment
    per: Scharenberg, C, et al.
    Publicat: (2011)

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