An enamine controlling group for rhodium-catalyzed intermolecular hydroacylation

An enamine-controlled hydroacylation of alkynes using a rhodium(I)/dppe catalyst system is described. The reaction is highly selective, forming the linear enaminone products as single regioisomers in all examples. In situ hydrolysis of the enamine functionality generated α-substituted 1,3-diketone p...

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Main Authors: Straker, R, Formica, M, Lupton, J, Niu, J, Willis, M
格式: Journal article
出版: Elsevier 2018