The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cells

The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cells

The EWS-ERG fusion protein is found in human sarcomas with the chromosomal translocation t(21;22)(q22;q12), where the translocation is considered to be an initiating event in sarcoma formation within uncommitted mesenchymal cells, probably long-lived progenitors capable of self renewal. The fusion p...

书目详细资料
Main Authors:	Codrington, R, Pannell, R, Forster, A, Drynan, L, Daser, A, Lobato, N, Metzler, M, Rabbitts, T
格式:	Journal article
语言:	English
出版:	Public Library of Science 2005

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