The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cells

The EWS-ERG fusion protein is found in human sarcomas with the chromosomal translocation t(21;22)(q22;q12), where the translocation is considered to be an initiating event in sarcoma formation within uncommitted mesenchymal cells, probably long-lived progenitors capable of self renewal. The fusion p...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Codrington, R, Pannell, R, Forster, A, Drynan, L, Daser, A, Lobato, N, Metzler, M, Rabbitts, T
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: Public Library of Science 2005