Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.
Biallelic CEBPA mutations and FMS-like tyrosine kinase receptor 3 (FLT3) length mutations are frequently identified in human acute myeloid leukemia (AML) with normal cytogenetics. However, the molecular and cellular mechanisms of oncogene cooperation remain unclear because of a lack of disease model...
Autori principali: | Reckzeh, K, Bereshchenko, O, Mead, A, Rehn, M, Kharazi, S, Jacobsen, SE, Nerlov, C, Cammenga, J |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2012
|
Documenti analoghi
Documenti analoghi
-
Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.
di: Reckzeh, K, et al.
Pubblicazione: (2012) -
ROLE OF BIALLELIC C/EBPALPHA MUTATIONS AND FLT-3 ITD IN INITIATION AND MAINTENANCE OF AML
di: Reckzeh, K, et al.
Pubblicazione: (2010) -
Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.
di: Bereshchenko, O, et al.
Pubblicazione: (2009) -
Germline counterparts of oncogenic mutations: who gives a JAK?.
di: Mead, A, et al.
Pubblicazione: (2013) -
Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.
di: Kharazi, S, et al.
Pubblicazione: (2011)