Molecular and cellular effects of oncogene cooperation in a genetically accurate AML mouse model.

Biallelic CEBPA mutations and FMS-like tyrosine kinase receptor 3 (FLT3) length mutations are frequently identified in human acute myeloid leukemia (AML) with normal cytogenetics. However, the molecular and cellular mechanisms of oncogene cooperation remain unclear because of a lack of disease model...

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Hlavní autoři: Reckzeh, K, Bereshchenko, O, Mead, A, Rehn, M, Kharazi, S, Jacobsen, SE, Nerlov, C, Cammenga, J
Médium: Journal article
Jazyk:English
Vydáno: 2012