The traceless Staudinger ligation for indirect 18F-radiolabelling.
The Staudinger ligation of phosphine-substituted thioesters with (18)F-fluoroethylazide has been successfully applied to access (18)F-labelled molecules in radiochemical yields superior to 95%; the first fluorous variant of a Staudinger radio-ligation has been validated.
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
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2011
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_version_ | 1797090368188055552 |
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author | Carroll, L Boldon, S Bejot, R Moore, J Declerck, J Gouverneur, V |
author_facet | Carroll, L Boldon, S Bejot, R Moore, J Declerck, J Gouverneur, V |
author_sort | Carroll, L |
collection | OXFORD |
description | The Staudinger ligation of phosphine-substituted thioesters with (18)F-fluoroethylazide has been successfully applied to access (18)F-labelled molecules in radiochemical yields superior to 95%; the first fluorous variant of a Staudinger radio-ligation has been validated. |
first_indexed | 2024-03-07T03:17:34Z |
format | Journal article |
id | oxford-uuid:b650447f-461c-4608-9240-69cd4ebecbf0 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T03:17:34Z |
publishDate | 2011 |
record_format | dspace |
spelling | oxford-uuid:b650447f-461c-4608-9240-69cd4ebecbf02022-03-27T04:40:07ZThe traceless Staudinger ligation for indirect 18F-radiolabelling.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b650447f-461c-4608-9240-69cd4ebecbf0EnglishSymplectic Elements at Oxford2011Carroll, LBoldon, SBejot, RMoore, JDeclerck, JGouverneur, VThe Staudinger ligation of phosphine-substituted thioesters with (18)F-fluoroethylazide has been successfully applied to access (18)F-labelled molecules in radiochemical yields superior to 95%; the first fluorous variant of a Staudinger radio-ligation has been validated. |
spellingShingle | Carroll, L Boldon, S Bejot, R Moore, J Declerck, J Gouverneur, V The traceless Staudinger ligation for indirect 18F-radiolabelling. |
title | The traceless Staudinger ligation for indirect 18F-radiolabelling. |
title_full | The traceless Staudinger ligation for indirect 18F-radiolabelling. |
title_fullStr | The traceless Staudinger ligation for indirect 18F-radiolabelling. |
title_full_unstemmed | The traceless Staudinger ligation for indirect 18F-radiolabelling. |
title_short | The traceless Staudinger ligation for indirect 18F-radiolabelling. |
title_sort | traceless staudinger ligation for indirect 18f radiolabelling |
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