Fibroblasts prevent apoptosis of IL-2-deprived T cells without inducing proliferation: a selective effect on Bcl-XL expression.

Fibroblasts prevent apoptosis of IL-2-deprived T cells without inducing proliferation: a selective effect on Bcl-XL expression.

The apoptosis of human cytokine-deprived activated T cells can be prevented by a soluble mediator secreted by fibroblasts, epithelial and endothelial cells, and this rescue occurs with fibroblasts from different species. Fractionation of W138 fibroblast-conditioned medium indicated that the survival...

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Bibliographic Details
Main Authors:	Gombert, W, Borthwick, N, Wallace, D, Hyde, H, Bofill, M, Pilling, D, Beverley, P, Janossy, G, Salmon, M, Akbar, A
Format:	Journal article
Language:	English
Published:	1996

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