Creatine kinase-deficient hearts exhibit increased susceptibility to ischemia-reperfusion injury and impaired calcium homeostasis.

The creatine kinase (CK) system is involved in the rapid transport of high-energy phosphates from the mitochondria to the sites of maximal energy requirements such as myofibrils and sarcolemmal ion pumps. Hearts of mice with a combined knockout of cytosolic M-CK and mitochondrial CK (M/Mito-CK(-/-))...

詳細記述

書誌詳細
主要な著者: Spindler, M, Meyer, K, Strömer, H, Leupold, A, Boehm, E, Wagner, H, Neubauer, S
フォーマット: Journal article
言語:English
出版事項: 2004