Studies on ternary metallo-beta lactamase-inhibitor complexes using electrospray ionization mass spectrometry.

Studies on ternary metallo-beta lactamase-inhibitor complexes using electrospray ionization mass spectrometry.

Metallo-beta-lactamases (MBLs) are targets for medicinal chemistry as they mediate bacterial resistance to beta-lactam antibiotics. Electrospray-ionization mass spectrometry (ESI-MS) was used to study the inhibition by a set of mercaptocarboxylates of two representative MBLs with different optimal m...

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Bibliographic Details
Main Authors:	Selevsek, N, Tholey, A, Heinzle, E, Liénard, B, Oldham, N, Schofield, C, Heinz, U, Adolph, H, Frère, J
Format:	Journal article
Language:	English
Published:	2006

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