Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann-Pick disease type C.

Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann-Pick disease type C.

Invariant natural killer T (iNKT) cells are a specialised subset of T cells that are restricted to the MHC class I like molecule, CD1d. The ligands for iNKT cells are lipids, with the canonical superagonist being α-galactosylceramide, a non-mammalian glycosphingolipid. Trafficking of CD1d through th...

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Bibliographic Details
Main Authors: Speak, A, Platt, N, Salio, M, te Vruchte, D, Smith, D, Shepherd, D, Veerapen, N, Besra, G, Yanjanin, N, Simmons, L, Imrie, J, Wraith, J, Lachmann, R, Hartung, R, Runz, H, Mengel, E, Beck, M, Hendriksz, C, Porter, F, Cerundolo, V, Platt, F
Format: Journal article
Language:English
Published: 2012

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