Invariant natural killer T cells are not affected by lysosomal storage in patients with Niemann-Pick disease type C.
Invariant natural killer T (iNKT) cells are a specialised subset of T cells that are restricted to the MHC class I like molecule, CD1d. The ligands for iNKT cells are lipids, with the canonical superagonist being α-galactosylceramide, a non-mammalian glycosphingolipid. Trafficking of CD1d through th...
Main Authors: | Speak, A, Platt, N, Salio, M, te Vruchte, D, Smith, D, Shepherd, D, Veerapen, N, Besra, G, Yanjanin, N, Simmons, L, Imrie, J, Wraith, J, Lachmann, R, Hartung, R, Runz, H, Mengel, E, Beck, M, Hendriksz, C, Porter, F, Cerundolo, V, Platt, F |
---|---|
格式: | Journal article |
语言: | English |
出版: |
2012
|
相似书籍
-
A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma.
由: Jiang, X, et al.
出版: (2011) -
Niemann-Pick Type C disease: characterizing lipid levels in patients with variant lysosomal cholesterol storage[S]
由: Carolina Tängemo, et al.
出版: (2011-04-01) -
Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials
由: Cortina-Borja, M, et al.
出版: (2018) -
Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials
由: Mario Cortina-Borja, et al.
出版: (2018-08-01) -
Plasma phosphorylated-tau217 is increased in Niemann–Pick disease type C
由: Gonzalez-Ortiz, F, et al.
出版: (2024)