Asymmetric synthesis of (-)-codonopsinine

The asymmetric synthesis of (-)-codonopsinine was achieved in 7 steps (from commercially available tert-butyl crotonate) in 5% overall yield and >99:1 dr. The key step in this synthesis involved ring-closing iodoamination of a functionalised homoallylic amine, which occurred with concomitant...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Davies, S, Lee, J, Roberts, P, Thomson, J, West, C
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2011