Intracellular antibody-caspase-mediated cell killing: an approach for application in cancer therapy.

Antibodies have been expressed inside cells in an attempt to ablate the function of oncogene products. To make intracellular antibodies more generally applicable and effective in cancer therapy, we have devised a method in which programmed cell death or apoptosis can be triggered by specific antibod...

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Bibliographic Details
Main Authors: Tse, E, Rabbitts, T
Format: Journal article
Language:English
Published: 2000