Base excision repair targets for cancer therapy.

Base excision repair targets for cancer therapy.

Cellular DNA repair is a frontline system that is responsible for maintaining genome integrity and thus preventing premature aging and cancer by repairing DNA lesions and strand breaks caused by endogenous and exogenous mutagens. However, it is also the principal cellular system in cancer cells that...

Podrobná bibliografie
Hlavní autor:	Dianov, G
Médium:	Journal article
Jazyk:	English
Vydáno:	2011

Podobné jednotky

Targeting base excision repair to improve cancer therapies.
Autor: Sharma, R, a další
Vydáno: (2007)

Monitoring base excision repair by in vitro assays.
Autor: Dianov, G
Vydáno: (2003)

Base excision repair fidelity in normal and cancer cells.
Autor: Chan, K, a další
Vydáno: (2006)

Mammalian base excision repair: the forgotten archangel.
Autor: Dianov, G, a další
Vydáno: (2013)

Co-ordination of base excision repair and genome stability.
Autor: Parsons, J, a další
Vydáno: (2013)

DNA repair fidelity of base excision repair pathways in human cell extracts.
Autor: Zhang, Q, a další
Vydáno: (2005)

The emerging role of Mule and ARF in the regulation of base excision repair.
Autor: Khoronenkova, S, a další
Vydáno: (2011)

The emerging role of Mule and ARF in the regulation of base excision repair
Autor: Khoronenkova, S, a další
Vydáno: (2011)

In vitro base excision repair using mammalian cell extracts.
Autor: Parsons, J, a další
Vydáno: (2012)

Orchestration of base excision repair by controlling the rates of enzymatic activities.
Autor: Allinson, S, a další
Vydáno: (2004)

DNA base excision repair: the Achilles' heel of tumour cells and their microenvironment?
Autor: Poletto, M, a další
Vydáno: (2017)

Exchangeability of mammalian DNA ligases between base excision repair pathways.
Autor: Sleeth, K, a další
Vydáno: (2004)

Monitoring base excision repair proteins on damaged DNA using human cell extracts.
Autor: Parsons, J, a další
Vydáno: (2004)

p53 coordinates base excision repair to prevent genomic instability
Autor: Poletto, M, a další
Vydáno: (2016)

Targeting the 8-oxodG Base Excision Repair Pathway for Cancer Therapy
Autor: Anna Piscone, a další
Vydáno: (2025-01-01)

Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability
Autor: Markkanen, E, a další
Vydáno: (2015)

XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
Autor: Dianova, I, a další
Vydáno: (2004)

CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.
Autor: Parsons, J, a další
Vydáno: (2008)

DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
Autor: Parsons, J, a další
Vydáno: (2005)

Isolation of a small molecule inhibitor of DNA base excision repair.
Autor: Madhusudan, S, a další
Vydáno: (2005)

Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair.
Autor: Chan, K, a další
Vydáno: (2007)

Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
Autor: Parsons, J, a další
Vydáno: (2009)

Role of Base Excision Repair in Innate Immune Cells and Its Relevance for Cancer Therapy
Autor: Shengyuan Zhao, a další
Vydáno: (2022-02-01)

Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
Autor: Poletto, M, a další
Vydáno: (2017)

Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients
Autor: Chen, X, a další
Vydáno: (2018)

USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
Autor: Parsons, J, a další
Vydáno: (2011)

Regulation of the base excision repair pathway
Autor: Fletcher, S, a další
Vydáno: (2017)

Base excision repair and the role of <it>MUTYH</it>
Autor: Kairupan Carla, a další
Vydáno: (2007-12-01)

Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
Autor: Yang, J, a další
Vydáno: (2010)

Exploiting Base Excision Repair to Improve Therapeutic Approaches for Pancreatic Cancer
Autor: George eSharbeen, a další
Vydáno: (2015-03-01)

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.
Autor: Ström, C, a další
Vydáno: (2011)

Bacillus Calmette-Guerin Increases Base Excision Repair in Bladder Cancer Cells
Autor: Selçuk Keskin, a další
Vydáno: (2021-03-01)

Base Sequence Context Effects on Nucleotide Excision Repair
Autor: Yuqin Cai, a další
Vydáno: (2010-01-01)

Haglund Excision and Suture Bridge Repair
Autor: Albert T. Anastasio MD, a další
Vydáno: (2023-02-01)

Functional DNA repair capacity assays : a focus on base excision repair
Autor: Chaim, Isaac Alexander
Vydáno: (2016)

Lycopene Protects against Smoking-Induced Lung Cancer by Inducing Base Excision Repair
Autor: Junrui Cheng, a další
Vydáno: (2020-07-01)

DNA Damage and Base Excision Repair in Mitochondria and Their Role in Aging
Autor: Ricardo Gredilla
Vydáno: (2011-01-01)

OGG1 in Lung—More than Base Excision Repair
Autor: Xiaodi Ma, a další
Vydáno: (2022-05-01)

The base excision repair pathway is required for efficient lentivirus integration.
Autor: Kristine E Yoder, a další
Vydáno: (2011-03-01)

DNA repair in cancer stem cells as a factor for glioma resistance to radiotherapy
Autor: Yu. S. Makusheva, a další
Vydáno: (2015-07-01)