Base excision repair targets for cancer therapy.

Base excision repair targets for cancer therapy.

Cellular DNA repair is a frontline system that is responsible for maintaining genome integrity and thus preventing premature aging and cancer by repairing DNA lesions and strand breaks caused by endogenous and exogenous mutagens. However, it is also the principal cellular system in cancer cells that...

Detaylı Bibliyografya
Yazar:	Dianov, G
Materyal Türü:	Journal article
Dil:	English
Baskı/Yayın Bilgisi:	2011

Benzer Materyaller

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The emerging role of Mule and ARF in the regulation of base excision repair
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In vitro base excision repair using mammalian cell extracts.
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XRCC1-DNA polymerase beta interaction is required for efficient base excision repair.
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CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins.
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DNA polymerase beta promotes recruitment of DNA ligase III alpha-XRCC1 to sites of base excision repair.
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Overexpression of DNA polymerase beta results in an increased rate of frameshift mutations during base excision repair.
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Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
Yazar:: Parsons, J, ve diğerleri
Baskı/Yayın Bilgisi: (2009)

Role of Base Excision Repair in Innate Immune Cells and Its Relevance for Cancer Therapy
Yazar:: Shengyuan Zhao, ve diğerleri
Baskı/Yayın Bilgisi: (2022-02-01)

Modulation of proteostasis counteracts oxidative stress and affects DNA base excision repair capacity in ATM-deficient cells
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Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients
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USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase β.
Yazar:: Parsons, J, ve diğerleri
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Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.
Yazar:: Yang, J, ve diğerleri
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Regulation of the base excision repair pathway
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Base excision repair and the role of <it>MUTYH</it>
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Exploiting Base Excision Repair to Improve Therapeutic Approaches for Pancreatic Cancer
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Baskı/Yayın Bilgisi: (2015-03-01)

CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.
Yazar:: Ström, C, ve diğerleri
Baskı/Yayın Bilgisi: (2011)

Bacillus Calmette-Guerin Increases Base Excision Repair in Bladder Cancer Cells
Yazar:: Selçuk Keskin, ve diğerleri
Baskı/Yayın Bilgisi: (2021-03-01)

Base Sequence Context Effects on Nucleotide Excision Repair
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The Base Excision Repair Pathway in the Nematode Caenorhabditis elegans
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Haglund Excision and Suture Bridge Repair
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Baskı/Yayın Bilgisi: (2023-02-01)

Functional DNA repair capacity assays : a focus on base excision repair
Yazar:: Chaim, Isaac Alexander
Baskı/Yayın Bilgisi: (2016)

Lycopene Protects against Smoking-Induced Lung Cancer by Inducing Base Excision Repair
Yazar:: Junrui Cheng, ve diğerleri
Baskı/Yayın Bilgisi: (2020-07-01)

Defective base excision repair in the response to DNA damaging agents in triple negative breast cancer.
Yazar:: Kevin J Lee, ve diğerleri
Baskı/Yayın Bilgisi: (2019-01-01)

DNA repair in cancer stem cells as a factor for glioma resistance to radiotherapy
Yazar:: Yu. S. Makusheva, ve diğerleri
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DNA Damage and Base Excision Repair in Mitochondria and Their Role in Aging
Yazar:: Ricardo Gredilla
Baskı/Yayın Bilgisi: (2011-01-01)