Pleckstrin Homology Domain Interacting Protein (PHIP); A Target Enabling Package

A description of the materials and methods is included within the TEP datasheet. SGC Oxford has expressed, purified and crystallized the second bromodomain of PHIP as part of the probe programme. Fragment screening and X-ray crystallography identified binders, some of which optimised to uM affinity....

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Détails bibliographiques
Auteur principal: Brennan, P
Autres auteurs: Cox, O
Format: Dataset
Publié: University of Oxford 2018
Sujets: