A study of δ-globin gene mutations in the UK population: identification of three novel variants and development of a novel DNA test for Hb A'2.

We report here the spectrum of δ-globin gene mutations found in the UK population. Nine different δ chain variants and two δ-thalassemia (δ-thal) mutations were characterized in a study of 127 alleles in patients with either a low Hb A2 value or a split Hb A2 peak on high performance liquid chromato...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Khalil, MS, Marouf, S, Element, D, Timbs, A, Gallienne, A, Schuh, A, Old, J, Henderson, S
Format: Journal article
Sprache:English
Veröffentlicht: Informa Healthcare 2014