Cutting edge: anti-CD154 therapeutic antibodies induce infectious transplantation tolerance.

Cutting edge: anti-CD154 therapeutic antibodies induce infectious transplantation tolerance.

Nondepleting anti-CD154 (CD40 ligand) mAbs have proven effective in inducing transplantation tolerance in rodents and primates. In the induction phase, anti-CD154 Ab therapy is known to enhance apoptosis of Ag reactive T cells. However, this may not be the sole explanation for tolerance, as we show...

Полное описание

Библиографические подробности
Главные авторы:	Graca, L, Honey, K, Adams, E, Cobbold, S, Waldmann, H
Формат:	Journal article
Язык:	English
Опубликовано:	2000

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