Filter flexibility in a mammalian K channel: models and simulations of Kir6.2 mutants.

Filter flexibility in a mammalian K channel: models and simulations of Kir6.2 mutants.

The single-channel conductance varies significantly between different members of the inward rectifier (Kir) family of potassium channels. Mutations at three sites in Kir6.2 have been shown to produce channels with reduced single-channel conductance, the largest reduction (to 40% of wild-type) being...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Capener, C, Proks, P, Ashcroft, F, Sansom, MS
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2003

Παρόμοια τεκμήρια

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Mapping the architecture of the ATP-binding site of Kir6.2
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Parametrisation of the free energy of ATP binding to wild-type and mutant Kir6.2 potassium channels.
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Έκδοση: (2013)