Filter flexibility in a mammalian K channel: models and simulations of Kir6.2 mutants.

Filter flexibility in a mammalian K channel: models and simulations of Kir6.2 mutants.

The single-channel conductance varies significantly between different members of the inward rectifier (Kir) family of potassium channels. Mutations at three sites in Kir6.2 have been shown to produce channels with reduced single-channel conductance, the largest reduction (to 40% of wild-type) being...

书目详细资料
Main Authors:	Capener, C, Proks, P, Ashcroft, F, Sansom, MS
格式:	Journal article
语言:	English
出版:	2003

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