Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor alpha monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis.

OBJECTIVE: To evaluate the efficacy, pharmacokinetics, immunogenicity, and safety of multiple infusions of a chimeric monoclonal anti-tumor necrosis factor alpha antibody (cA2) (infliximab; Remicade, Centocor, Malvern, PA) given alone or in combination with low-dose methotrexate (MTX) in rheumatoid...

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Main Authors: Maini, R, Breedveld, F, Kalden, JR, Smolen, J, Davis, D, Macfarlane, J, Antoni, C, Leeb, B, Elliott, M, Woody, J, Schaible, T, Feldmann, M
格式: Journal article
语言:English
出版: 1998