POTENT INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A SPIROHYDANTOIN OF GLUCOPYRANOSE - FIRST PYRANOSE ANALOGS OF HYDANTOCIDIN
The synthesis of two epimeric spirohydantoins of glucopyranose provides the first examples of pyranose analogues of hydantocidin: molecular modelling correctly predicted that one of the epimers would be a potent inhibitor of glycogen phosphorylase. This is the first example of specific enzyme inhibi...
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التفاصيل البيبلوغرافية
| المؤلفون الرئيسيون: |
Bichard, C,
Mitchell, E,
Wormald, M,
Watson, K,
Johnson, L,
Zographos, S,
Koutra, D,
Oikonomakos, N,
Fleet, G |
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| التنسيق: | Journal article
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| منشور في: |
1995
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