Chemoselective formation and reaction of densely functionalised bicyclic tetramic acids and their biological activity

Weinreb amide derivatives of tetramates may be effectively accessed by chemoselective Dieckmann reaction, and further react with Grignards in a fully chemoselective reaction, giving rise to unsaturated acyl derivatives not easily available by other routes. These systems are strong chelators of calci...

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Autors principals: Moloney, M, Josa-Culleré, L, Thompson, A, Towers, C
Format: Journal article
Publicat: Wiley 2017