Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis

Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis

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<p style="text-align:justify;"> Adjunctive treatment to improve outcome from bacterial meningitis has centered on dexamethasone. Among Vietnamese patients with bacterial meningitis, cerebrospinal flu id (CSF) opening pressure and CSF:plasma glucose ratios were significantly improved...

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Bibliographic Details
Main Authors: Mai, N, Tuan, T, Wolbers, M, Hoang, D, Nga, T, Chau, T, Chuong, L, Sinh, D, Nghia, H, Phong, N, Phu, N, Diep, T, Hang, H, Chau, N, Farrar, J, Schultsz, C, Hien, T, Simmons, C
Format: Journal article
Language:English
Published: Oxford University Press 2009
Description
Summary:<p style="text-align:justify;"> Adjunctive treatment to improve outcome from bacterial meningitis has centered on dexamethasone. Among Vietnamese patients with bacterial meningitis, cerebrospinal flu id (CSF) opening pressure and CSF:plasma glucose ratios were significantly improved and levels of CSF cytokines interleukin (IL)-6, IL-8, and IL-10 and were all statistically significantly lower after treatment in patients who were randomized to dexamethasone, compared with levels in patients who received placebo. </p>

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