Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis

<p style="text-align:justify;"> Adjunctive treatment to improve outcome from bacterial meningitis has centered on dexamethasone. Among Vietnamese patients with bacterial meningitis, cerebrospinal flu id (CSF) opening pressure and CSF:plasma glucose ratios were significantly improved...

Full description

Bibliographic Details
Main Authors: Mai, N, Tuan, T, Wolbers, M, Hoang, D, Nga, T, Chau, T, Chuong, L, Sinh, D, Nghia, H, Phong, N, Phu, N, Diep, T, Hang, H, Chau, N, Farrar, J, Schultsz, C, Hien, T, Simmons, C
Format: Journal article
Language:English
Published: Oxford University Press 2009
_version_ 1826292758420127744
author Mai, N
Tuan, T
Wolbers, M
Hoang, D
Nga, T
Chau, T
Chuong, L
Sinh, D
Nghia, H
Phong, N
Phu, N
Diep, T
Hang, H
Chau, N
Farrar, J
Schultsz, C
Hien, T
Simmons, C
author_facet Mai, N
Tuan, T
Wolbers, M
Hoang, D
Nga, T
Chau, T
Chuong, L
Sinh, D
Nghia, H
Phong, N
Phu, N
Diep, T
Hang, H
Chau, N
Farrar, J
Schultsz, C
Hien, T
Simmons, C
author_sort Mai, N
collection OXFORD
description <p style="text-align:justify;"> Adjunctive treatment to improve outcome from bacterial meningitis has centered on dexamethasone. Among Vietnamese patients with bacterial meningitis, cerebrospinal flu id (CSF) opening pressure and CSF:plasma glucose ratios were significantly improved and levels of CSF cytokines interleukin (IL)-6, IL-8, and IL-10 and were all statistically significantly lower after treatment in patients who were randomized to dexamethasone, compared with levels in patients who received placebo. </p>
first_indexed 2024-03-07T03:19:38Z
format Journal article
id oxford-uuid:b6fe1766-dfc5-4562-9424-be5be4fcf44f
institution University of Oxford
language English
last_indexed 2024-03-07T03:19:38Z
publishDate 2009
publisher Oxford University Press
record_format dspace
spelling oxford-uuid:b6fe1766-dfc5-4562-9424-be5be4fcf44f2022-03-27T04:45:09ZImmunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitisJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b6fe1766-dfc5-4562-9424-be5be4fcf44fEnglishSymplectic Elements at OxfordOxford University Press2009Mai, NTuan, TWolbers, MHoang, DNga, TChau, TChuong, LSinh, DNghia, HPhong, NPhu, NDiep, THang, HChau, NFarrar, JSchultsz, CHien, TSimmons, C <p style="text-align:justify;"> Adjunctive treatment to improve outcome from bacterial meningitis has centered on dexamethasone. Among Vietnamese patients with bacterial meningitis, cerebrospinal flu id (CSF) opening pressure and CSF:plasma glucose ratios were significantly improved and levels of CSF cytokines interleukin (IL)-6, IL-8, and IL-10 and were all statistically significantly lower after treatment in patients who were randomized to dexamethasone, compared with levels in patients who received placebo. </p>
spellingShingle Mai, N
Tuan, T
Wolbers, M
Hoang, D
Nga, T
Chau, T
Chuong, L
Sinh, D
Nghia, H
Phong, N
Phu, N
Diep, T
Hang, H
Chau, N
Farrar, J
Schultsz, C
Hien, T
Simmons, C
Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis
title Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis
title_full Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis
title_fullStr Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis
title_full_unstemmed Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis
title_short Immunological and biochemical correlates of adjunctive dexamethasone in Vietnamese adults with bacterial meningitis
title_sort immunological and biochemical correlates of adjunctive dexamethasone in vietnamese adults with bacterial meningitis
work_keys_str_mv AT main immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT tuant immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT wolbersm immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT hoangd immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT ngat immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT chaut immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT chuongl immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT sinhd immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT nghiah immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT phongn immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT phun immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT diept immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT hangh immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT chaun immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT farrarj immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT schultszc immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT hient immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis
AT simmonsc immunologicalandbiochemicalcorrelatesofadjunctivedexamethasoneinvietnameseadultswithbacterialmeningitis