FtsK Is a DNA motor protein that activates chromosome dimer resolution by switching the catalytic state of the XerC and XerD recombinases.

FtsK acts at the bacterial division septum to couple chromosome segregation with cell division. We demonstrate that a truncated FtsK derivative, FtsK(50C), uses ATP hydrolysis to translocate along duplex DNA as a multimer in vitro, consistent with FtsK having an in vivo role in pumping DNA through t...

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Autors principals: Aussel, L, Barre, F, Aroyo, M, Stasiak, A, Sherratt, D
Format: Journal article
Idioma:English
Publicat: 2002

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