Mechanisms of resistance to antiangiogenesis therapy.
Angiogenesis, the formation of new blood vessels from existing vasculature, plays an essential role in tumour growth, invasion and metastasis. Vascular endothelial growth factor (VEGF) is one of the key factors responsible for its regulation. High expression of VEGF has been observed in many cancers...
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2010
|