Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity.
UNLABELLED: Broad T cell and B cell responses to multiple HCV antigens are observed early in individuals who control or clear HCV infection. The prevailing hypothesis has been that similar immune responses induced by prophylactic immunization would reduce acute virus replication and protect exposed...
Main Authors: | Rollier, C, Paranhos-Baccala, G, Verschoor, E, Verstrepen, B, Drexhage, J, Fagrouch, Z, Berland, J, Komurian-Pradel, F, Duverger, B, Himoudi, N, Staib, C, Meyr, M, Whelan, M, Whelan, J, Adams, VC, Adams, V, Larrea, E, Riezu, J, Lasarte, J, Bartosch, B, Cosset, F, Spaan, W, Diepolder, H, Pape, G |
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Format: | Journal article |
Language: | English |
Published: |
2007
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