Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance.

Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance.

Mechanisms for observed associations within the major histocompatibility complex (MHC) and autoimmune diseases including multiple sclerosis (MS) remain uncertain. Genotyping of the HLA Class II DRB1 locus in 4347 individuals from 873 multiplex families with MS highlights the genetic complexity of th...

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Autors principals:	Dyment, D, Herrera, B, Cader, M, Willer, C, Lincoln, MR, Sadovnick, A, Risch, N, Ebers, G
Format:	Journal article
Idioma:	English
Publicat:	2005

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