The APOE ɛ4 allele modulates brain white matter integrity in healthy adults.
The Apolipoprotein E (APOE) ɛ4 allele is the best-established genetic risk factor for sporadic Alzheimer's disease, and is also associated with structural gray matter and functional brain changes in healthy young, middle-aged and elderly subjects. Because APOE is implicated in brain mechanisms...
Main Authors: | Heise, V, Filippini, N, Ebmeier, K, Mackay, C |
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Format: | Journal article |
Language: | English |
Published: |
2011
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