The relationship between steroidogenic factor 1 and DAX-1 expression and in vitro gonadotropin secretion in human pituitary adenomas.

The relationship between steroidogenic factor 1 and DAX-1 expression and in vitro gonadotropin secretion in human pituitary adenomas.

The orphan nuclear receptors, steroidogenic factor 1 (SF-1) and DAX-1, are involved in gonadotroph differentiation, and SF-1 has been shown to activate the LH-beta and glycoprotein hormone alpha-subunit (alpha GSU) gene promoters. Pituitary adenomas from 34 patients [13 somatotroph tumors, 4 prolact...

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Bibliographic Details
Main Authors: Aylwin, S, Welch, J, Davey, C, Geddes, J, Wood, D, Besser, G, Grossman, AB, Monson, J, Burrin, J
Format: Journal article
Language:English
Published: 2001

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