Invariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice.

Invariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice.

Understanding the protective mechanism in the liver induced by recombinant vaccines against the pre-erythrocytic stages of malaria is important for vaccine development. Most studies in mice have focused on splenic and peripheral blood T cells and identified gamma interferon (IFN-gamma)-producing CD8...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Korten, S, Anderson, R, Hannan, C, Sheu, E, Sinden, R, Gadola, S, Taniguchi, M, Hill, A
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2005

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