Pathogenic protease expression in murine OA is critically dependent upon mechanical joint loading

Geahča maid

• MECHANICAL LOAD DRIVES INFLAMMATORY GENE EXPRESSION AND DISEASE IN MURINE OA
  Dahkki: Burleigh, A, et al.
  Almmustuhtton: (2010)
• IL18 IS SECRETED UPON JOINT INJURY AND IS A KEY PATHOGENIC CYTOKINE IN MURINE OSTEOARTHRITIS
  Dahkki: Vincent, T, et al.
  Almmustuhtton: (2014)
• Joint immobilization prevents murine osteoarthritis and reveals the highly mechanosensitive nature of protease expression in vivo.
  Dahkki: Burleigh, A, et al.
  Almmustuhtton: (2012)
• ADAMTS4 and ADAMTS5 are upregulated early in the DMM model of murine OA
  Dahkki: Burleigh, A, et al.
  Almmustuhtton: (2009)
• PARTIAL JOINT IMMOBILISATION PROTECTS AGAINST OA AND REVEALS DISTINCT BIOMECHANICAL THRESHOLDS IN THE JOINT
  Dahkki: Burleigh, A, et al.
  Almmustuhtton: (2010)