The prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door survey
A two-phase survey of epilepsy was conducted in selected villages in Mundri West and East Counties (26 June–8 July, 2021), an onchocerciasis-endemic area in Western Equatoria State in South Sudan. In the first phase, households were visited by a trained research team to identify persons suspected to...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
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MDPI
2022
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| _version_ | 1826308185454018560 |
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| author | Jada, SR Dusabimana, A Abd-Elfarag, G Okaro, S Brusselaers, N Carter, JY Logora, MY Rovarini, JM Newton, CR Colebunders, R |
| author_facet | Jada, SR Dusabimana, A Abd-Elfarag, G Okaro, S Brusselaers, N Carter, JY Logora, MY Rovarini, JM Newton, CR Colebunders, R |
| author_sort | Jada, SR |
| collection | OXFORD |
| description | A two-phase survey of epilepsy was conducted in selected villages in Mundri West and East Counties (26 June–8 July, 2021), an onchocerciasis-endemic area in Western Equatoria State in South Sudan. In the first phase, households were visited by a trained research team to identify persons suspected to have epilepsy. In the second phase, persons suspected to have epilepsy were interviewed and examined by a clinician to confirm the diagnosis. A total of 364 households agreed to participate in the survey, amounting to 2588 individuals. The epilepsy screening questionnaire identified 91 (3.5%) persons with suspected epilepsy, of whom the diagnosis of epilepsy was confirmed by a clinician in 86 (94.5%). The overall prevalence of confirmed epilepsy was 3.3% (95% CI: 2.7–4.1%), and of nodding syndrome was 0.9% (95% CI: 0.6–1.4%). In 61 (16.8%) households there was at least one person with epilepsy. Only 1212 (46.9%) of 2583 people took ivermectin during the last distribution round in 2021. The annual epilepsy incidence was 77.3/100,000 (95% CI: 9.4–278.9/100,000) and the annual epilepsy mortality was 251.2/100,000 (95% CI: 133.8–428.7/100,000). In conclusion, a high prevalence and incidence of epilepsy was observed in villages in Mundri. Urgent action is needed to prevent children from developing onchocerciasis-associated epilepsy by strengthening the local onchocerciasis-elimination programme. |
| first_indexed | 2024-03-07T07:14:16Z |
| format | Journal article |
| id | oxford-uuid:b7b98f1a-d098-4874-b643-4dfe31b17f99 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T07:14:16Z |
| publishDate | 2022 |
| publisher | MDPI |
| record_format | dspace |
| spelling | oxford-uuid:b7b98f1a-d098-4874-b643-4dfe31b17f992022-07-21T11:48:00ZThe prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door surveyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b7b98f1a-d098-4874-b643-4dfe31b17f99EnglishSymplectic ElementsMDPI2022Jada, SRDusabimana, AAbd-Elfarag, GOkaro, SBrusselaers, NCarter, JYLogora, MYRovarini, JMNewton, CRColebunders, RA two-phase survey of epilepsy was conducted in selected villages in Mundri West and East Counties (26 June–8 July, 2021), an onchocerciasis-endemic area in Western Equatoria State in South Sudan. In the first phase, households were visited by a trained research team to identify persons suspected to have epilepsy. In the second phase, persons suspected to have epilepsy were interviewed and examined by a clinician to confirm the diagnosis. A total of 364 households agreed to participate in the survey, amounting to 2588 individuals. The epilepsy screening questionnaire identified 91 (3.5%) persons with suspected epilepsy, of whom the diagnosis of epilepsy was confirmed by a clinician in 86 (94.5%). The overall prevalence of confirmed epilepsy was 3.3% (95% CI: 2.7–4.1%), and of nodding syndrome was 0.9% (95% CI: 0.6–1.4%). In 61 (16.8%) households there was at least one person with epilepsy. Only 1212 (46.9%) of 2583 people took ivermectin during the last distribution round in 2021. The annual epilepsy incidence was 77.3/100,000 (95% CI: 9.4–278.9/100,000) and the annual epilepsy mortality was 251.2/100,000 (95% CI: 133.8–428.7/100,000). In conclusion, a high prevalence and incidence of epilepsy was observed in villages in Mundri. Urgent action is needed to prevent children from developing onchocerciasis-associated epilepsy by strengthening the local onchocerciasis-elimination programme. |
| spellingShingle | Jada, SR Dusabimana, A Abd-Elfarag, G Okaro, S Brusselaers, N Carter, JY Logora, MY Rovarini, JM Newton, CR Colebunders, R The prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door survey |
| title | The prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door survey |
| title_full | The prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door survey |
| title_fullStr | The prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door survey |
| title_full_unstemmed | The prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door survey |
| title_short | The prevalence of onchocerciasis-associated epilepsy in Mundri West and East Counties, South Sudan: A door-to-door survey |
| title_sort | prevalence of onchocerciasis associated epilepsy in mundri west and east counties south sudan a door to door survey |
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