Is the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literature
Over the last 20 years there have been 32 reports of carbapenem-resistant organisms in the hospital water environment, with half of these occurring since 2010. The majority of these reports have described associated clinical outbreaks in the intensive care setting, affecting the critically ill and t...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
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Oxford University Press
2017
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| _version_ | 1826292909800947712 |
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| author | Kizny-Gordon, A Mathers, A Cheong, E Gottlieb, T Kotay, S Walker, A Peto, T Crook, D Stoesser, N |
| author_facet | Kizny-Gordon, A Mathers, A Cheong, E Gottlieb, T Kotay, S Walker, A Peto, T Crook, D Stoesser, N |
| author_sort | Kizny-Gordon, A |
| collection | OXFORD |
| description | Over the last 20 years there have been 32 reports of carbapenem-resistant organisms in the hospital water environment, with half of these occurring since 2010. The majority of these reports have described associated clinical outbreaks in the intensive care setting, affecting the critically ill and the immunocompromised. Drains, sinks and faucets were most frequently colonized, and Pseudomonas aeruginosa the predominant organism. IMP, KPC and VIM were the most common carbapenemases found. Molecular typing was performed in almost all studies, with pulse field gel electrophoresis being most commonly used. Seventy-two percent of studies reported controlling outbreaks, of which just over one-third eliminated the organism from the water environment. A combination of interventions appears to be most successful, including reinforcement of general infection control measures, alongside chemical disinfection. The most appropriate disinfection method however remains unclear, and it is likely that replacement of colonized water reservoirs may be required for long-term clearance. |
| first_indexed | 2024-03-07T03:21:58Z |
| format | Journal article |
| id | oxford-uuid:b7ba9011-d7ae-4d6f-a173-200b9f731102 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T03:21:58Z |
| publishDate | 2017 |
| publisher | Oxford University Press |
| record_format | dspace |
| spelling | oxford-uuid:b7ba9011-d7ae-4d6f-a173-200b9f7311022022-03-27T04:50:51ZIs the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literatureJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:b7ba9011-d7ae-4d6f-a173-200b9f731102Symplectic Elements at OxfordOxford University Press2017Kizny-Gordon, AMathers, ACheong, EGottlieb, TKotay, SWalker, APeto, TCrook, DStoesser, NOver the last 20 years there have been 32 reports of carbapenem-resistant organisms in the hospital water environment, with half of these occurring since 2010. The majority of these reports have described associated clinical outbreaks in the intensive care setting, affecting the critically ill and the immunocompromised. Drains, sinks and faucets were most frequently colonized, and Pseudomonas aeruginosa the predominant organism. IMP, KPC and VIM were the most common carbapenemases found. Molecular typing was performed in almost all studies, with pulse field gel electrophoresis being most commonly used. Seventy-two percent of studies reported controlling outbreaks, of which just over one-third eliminated the organism from the water environment. A combination of interventions appears to be most successful, including reinforcement of general infection control measures, alongside chemical disinfection. The most appropriate disinfection method however remains unclear, and it is likely that replacement of colonized water reservoirs may be required for long-term clearance. |
| spellingShingle | Kizny-Gordon, A Mathers, A Cheong, E Gottlieb, T Kotay, S Walker, A Peto, T Crook, D Stoesser, N Is the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literature |
| title | Is the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literature |
| title_full | Is the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literature |
| title_fullStr | Is the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literature |
| title_full_unstemmed | Is the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literature |
| title_short | Is the hospital water environment a reservoir for carbapenem-resistant organisms causing hospital-acquired infections? A systematic review of the literature |
| title_sort | is the hospital water environment a reservoir for carbapenem resistant organisms causing hospital acquired infections a systematic review of the literature |
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