Partial leptin deficiency and human adiposity.
The adipocyte-derived hormone leptin is crucial for energy homeostasis in mammals; mice and humans without it suffer from a voracious appetite and extreme obesity. The effect on energy balance of variations in plasma leptin above a minimal threshold is uncertain, however, particularly in humans. Her...
Main Authors: | Farooqi, I, Keogh, J, Kamath, S, Jones, S, Gibson, W, Trussell, R, Jebb, SA, Lip, G, O'Rahilly, S |
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Format: | Journal article |
Language: | English |
Published: |
2001
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