Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals.

Complete cloning of the Duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals.

The 14 kb human Duchenne muscular dystrophy (DMD) cDNA corresponding to a complete representation of the fetal skeletal muscle transcript has been cloned. The DMD transcript is formed by at least 60 exons which have been mapped relative to various reference points within Xp21. The first half of the...

Full description

Bibliographic Details
Main Authors:	Koenig, M, Hoffman, E, Bertelson, C, Monaco, A, Feener, C, Kunkel, L
Format:	Journal article
Language:	English
Published:	1987

Similar Items

Molecular studies of progressive muscular dystrophy (Duchenne).
by: Kunkel, L, et al.
Published: (1987)

THE GIANT DUCHENNE MUSCULAR-DYSTROPHY GENE AND ITS PROTEIN PRODUCT
by: Koenig, M, et al.
Published: (1988)

Transition from childhood to adulthood in Duchenne muscular dystrophy (DMD)
by: Rodger Sunil, et al.
Published: (2012-11-01)

Assessment of diaphragmatic thickness by ultrasonography in Duchenne muscular dystrophy (DMD) patients.
by: Marianna Laviola, et al.
Published: (2018-01-01)

A novel canine model for Duchenne muscular dystrophy (DMD): single nucleotide deletion in DMD gene exon 20
by: Sara Mata López, et al.
Published: (2018-05-01)

Molecular genetics of Duchenne muscular dystrophy.
by: Kunkel, L, et al.
Published: (1986)

Conservation of the Duchenne muscular dystrophy gene in mice and humans.
by: Hoffman, E, et al.
Published: (1987)

Targeting Duchenne muscular dystrophy by skipping DMD exon 45 with base editors
by: Michael Gapinske, et al.
Published: (2023-09-01)

Localization and cloning of Xp21 deletion breakpoints involved in muscular dystrophy.
by: Monaco, A, et al.
Published: (1987)

Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy gene.
by: Monaco, A, et al.
Published: (1986)

Localisation of Xp21 meiotic exchange points in Duchenne muscular dystrophy families.
by: Bertelson, C, et al.
Published: (1986)

Identification of Two Novel Variants of the DMD Gene in Chinese Families with Duchenne Muscular Dystrophy
by: Wu J, et al.
Published: (2023-08-01)

Chronic hypoxia impairs muscle function in the Drosophila model of Duchenne's muscular dystrophy (DMD).
by: Matias Mosqueira, et al.
Published: (2010-10-01)

Ventilatory chemosensory drive is blunted in the mdx mouse model of Duchenne Muscular Dystrophy (DMD).
by: Matias Mosqueira, et al.
Published: (2013-01-01)

A fleeting glimpse of functional benefit of the complete DMD gene in a large animal model of Duchenne muscular dystrophy
by: Eric P. Hoffman
Published: (2023-09-01)

Cloning of the Duchenne/Becker muscular dystrophy locus.
by: Monaco, A, et al.
Published: (1988)

Meaningful changes in motor function in Duchenne muscular dystrophy (DMD): A multi-center study
by: Muntoni, F, et al.
Published: (2024)

Analysis of the transcriptional control of utrophin promoters as a therapeutic strategy for Duchenne muscular dystrophy (DMD).
by: Perkins, K, et al.
Published: (2000)

Perspectives on Everyday Life Challenges of Danish Young People With Duchenne Muscular Dystrophy (DMD) on Corticosteroids
by: Charlotte Handberg, et al.
Published: (2022-04-01)

Screening of Duchenne muscular dystrophy (DMD) mutations and investigating its mutational mechanism in Chinese patients.
by: Chen Chen, et al.
Published: (2014-01-01)

Aquatic therapy for boys with Duchenne muscular dystrophy (DMD): an external pilot randomised controlled trial
by: Daniel Hind, et al.
Published: (2017-03-01)

New orally available compounds which modulate utrophin expression for the therapy of Duchenne muscular dystrophy (DMD)
by: Fairclough, R, et al.
Published: (2014)

Myopathologic trajectory in Duchenne muscular dystrophy (DMD) reveals lack of regeneration due to senescence in satellite cells
by: Nastasia Cardone, et al.
Published: (2023-10-01)

A family with autism and rare copy number variants disrupting the Duchenne/Becker muscular dystrophy gene DMD and TRPM3.
by: Pagnamenta, A, et al.
Published: (2011)

A family with autism and rare copy number variants disrupting the Duchenne/Becker muscular dystrophy gene DMD and TRPM3
by: Pagnamenta, A, et al.
Published: (2011)

A family with autism and rare copy number variants disrupting the Duchenne/Becker muscular dystrophy gene DMD and TRPM3.
by: Pagnamenta, A, et al.
Published: (2011)

Generation of two Duchenne muscular dystrophy patient-specific induced pluripotent stem cell lines DMD02 and DMD03 (MUNIi001-A and MUNIi003-A)
by: Sarka Jelinkova, et al.
Published: (2019-10-01)

An explanation for the phenotypic differences between patients bearing partial deletions of the DMD locus.
by: Monaco, A, et al.
Published: (1988)

DMD‐related muscular dystrophy in Cameroon: Clinical and genetic profiles
by: Edmond Wonkam‐Tingang, et al.
Published: (2020-08-01)

Preclinical studies of WVE-210201, an investigational stereopure antisense oligonucleotide in development for the treatment of patients with duchenne muscular dystrophy (DMD)
by: Panzara, M, et al.
Published: (2017)

Derivation of the Duchenne muscular dystrophy patient-derived induced pluripotent stem cell line lacking DMD exons 49 and 50 (CCMi001DMD-A-3, ∆49, ∆50)
by: Gabriella Spaltro, et al.
Published: (2017-12-01)

Clinical heterogeneity of duchenne muscular dystrophy (DMD): definition of sub-phenotypes and predictive criteria by long-term follow-up.
by: Isabelle Desguerre, et al.
Published: (2009-01-01)

Isolation and Characterization of Primary DMD Pig Muscle Cells as an <i>In Vitro</i> Model for Preclinical Research on Duchenne Muscular Dystrophy
by: Tina Donandt, et al.
Published: (2022-10-01)

A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy
by: Tatianna Wai Ying Wong, et al.
Published: (2020-09-01)

Development of a patient-reported outcome measure for upper limb function in Duchenne muscular dystrophy: DMD Upper Limb PROM
by: Klingels, K, et al.
Published: (2016)

Future clinical and biomarker development for SMTC1100, the first utrophin modulator to enter clinical trials for Duchenne Muscular Dystrophy (DMD)
by: Tinsley, J, et al.
Published: (2013)

Clinical study of DMD gene point mutation causing Becker muscular dystrophy
by: Ji-qing CAO, et al.
Published: (2015-06-01)

Novel Intronic Mutations Introduce Pseudoexons in DMD That Cause Muscular Dystrophy in Patients
by: Xinguo Lu, et al.
Published: (2021-04-01)

A multicenter comparison of quantification methods for antisense oligonucleotide-induced DMD exon 51 skipping in Duchenne muscular dystrophy cell cultures.
by: Monika Hiller, et al.
Published: (2018-01-01)

Gait Characterization in Duchenne Muscular Dystrophy (DMD) Using a Single-Sensor Accelerometer: Classical Machine Learning and Deep Learning Approaches
by: Albara Ah Ramli, et al.
Published: (2024-02-01)