Non-adherence in non-inferiority trials: pitfalls and recommendations

Non-adherence in non-inferiority trials can affect treatment effect estimates and often increases the chance of claiming non-inferiority under the standard intention-to-treat analysis. This article discusses the implications of different patterns of non-adherence in non-inferiority trials and offers...

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Main Authors: Mo, Y, Lim, C, Watson, JA, Nicholas J White, Cooper, BS
格式: Journal article
语言:English
出版: BMJ Publishing Group 2020