Elevated plasma concentrations of interferon (IFN)-gamma and the IFN-gamma-inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis.

Elevated plasma concentrations of interferon (IFN)-gamma and the IFN-gamma-inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis.

Interferon (IFN)-gamma plays an important role in the pathogenesis of sepsis. Production of IFN-gamma is stimulated by synergistic effects of interleukin (IL)-18, IL-12, and IL-15. To investigate the regulation of IFN-gamma production during severe gram-negative infection, the plasma concentrations...

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Bibliographic Details
Main Authors:	Lauw, F, Simpson, A, Prins, J, Smith, MD, Kurimoto, M, van Deventer, S, Speelman, P, Chaowagul, W, White, N, van der Poll, T
Format:	Journal article
Language:	English
Published:	1999

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