Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.

Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.

Susceptibility to tuberculosis is historically ascribed to an inadequate immune response that fails to control infecting mycobacteria. In zebrafish, we find that susceptibility to Mycobacterium marinum can result from either inadequate or excessive acute inflammation. Modulation of the leukotriene A...

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Bibliographic Details
Main Authors: Tobin, D, Roca, F, Oh, S, McFarland, R, Vickery, T, Ray, J, Ko, D, Zou, Y, Bang, N, Chau, T, Vary, J, Hawn, T, Dunstan, S, Farrar, J, Thwaites, G, King, M, Serhan, C, Ramakrishnan, L
Format: Journal article
Language:English
Published: 2012

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