Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment.
BACKGROUND: Chronic heart failure (CHF) is a major cause of morbidity and mortality that requires a novel approach to therapy. Perhexiline is an antianginal drug that augments glucose metabolism by blocking muscle mitochondrial free fatty acid uptake, thereby increasing metabolic efficiency. We asse...
मुख्य लेखकों: | Lee, L, Campbell, R, Scheuermann-Freestone, M, Taylor, R, Gunaruwan, P, Williams, L, Ashrafian, H, Horowitz, J, Fraser, A, Clarke, K, Frenneaux, M |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2005
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समान संसाधन
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Augmentation of glucose metabolism with perhexiline in non-ischaemic heart failure
द्वारा: Lee, L, और अन्य
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Perhexiline.
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Effects of perhexiline on ketone body and triglyceride synthesis in patients with refractory angina or heart failure
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Metabolic modulator perhexiline corrects energy deficiency and improves exercise capacity in symptomatic hypertrophic cardiomyopathy.
द्वारा: Abozguia, K, और अन्य
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Metabolic Modulation With Perhexiline Corrects Energy Deficiency and Improves Exercise Capacity in Symptomatic Hypertrophic Cardiomyopathy
द्वारा: Abozguia, K, और अन्य
प्रकाशित: (2009)