An in silico model of cytotoxic T-lymphocyte activation in the lymph node following short peptide vaccination
Tumour immunotherapy is dependent upon activation and expansion of tumour targetting immune cells, known as Cytotoxic T-Lymphocytes (CTLs). Cancer vaccines developed in the past have had limited success and the mechanisms resulting in failure are not well characterised. To elucidate these mechani...
| Main Authors: | , , , |
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| Format: | Journal article |
| Published: |
Royal Society
2018
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