An in silico model of cytotoxic T-lymphocyte activation in the lymph node following short peptide vaccination

An in silico model of cytotoxic T-lymphocyte activation in the lymph node following short peptide vaccination

Tumour immunotherapy is dependent upon activation and expansion of tumour targetting immune cells, known as Cytotoxic T-Lymphocytes (CTLs). Cancer vaccines developed in the past have had limited success and the mechanisms resulting in failure are not well characterised. To elucidate these mechani...

Bibliografiset tiedot
Päätekijät:	Brown, L, Gaffney, E, Wagg, J, Coles, M
Aineistotyyppi:	Journal article
Julkaistu:	Royal Society 2018

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